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Interaction of musleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing

In myotonic dystrophy (DM1), both inactivation of muscleblind proteins and increased levels of CUG-BP1 are reported. These events have been shown to contribute independently to aberrant splicing of a subset RNAs. We demonstrate that steady-state levels of the splice regulator, hnRNP H, are elevated...

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Main Authors: Paul, Sharan, Dansithong, Warunee, Kim, Dongho, Rossi, John, Webster, Nicholas J G, Comai, Lucio, Reddy, Sita
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570429/
https://ncbi.nlm.nih.gov/pubmed/16946708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601296
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