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Expression profiling of clonal lymphocyte cell cultures from Rett syndrome patients
BACKGROUND: More than 85% of Rett syndrome (RTT) patients have heterozygous mutations in the X-linked MECP2 gene which encodes methyl-CpG-binding protein 2, a transcriptional repressor that binds methylated CpG sites. Because MECP2 is subject to X chromosome inactivation (XCI), girls with RTT expres...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569822/ https://ncbi.nlm.nih.gov/pubmed/16859563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-7-61 |
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