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The Contributions of Protein Kinase A and Smoothened Phosphorylation to Hedgehog Signal Transduction in Drosophila melanogaster
Protein kinase A (PKA) silences the Hedgehog (Hh) pathway in Drosophila in the absence of ligand by phosphorylating the pathway's transcriptional effector, Cubitus interruptus (Ci). Smoothened (Smo) is essential for Hh signal transduction but loses activity if three specific PKA sites or adjace...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Copyright © 2006 by the Genetics Society of America
2006
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569721/ https://ncbi.nlm.nih.gov/pubmed/16783001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.061036 |
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