Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1α transcription and mitochondrial biogenesis in muscle cells

PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1α) is a master regulator of mitochondrial biogenesis and plays an important role in several other aspects of energy metabolism. To identify upstream regulators of PGC-1α gene transcription, 10,000 human full-length cDNAs were screened...

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Detalhes bibliográficos
Main Authors: Wu, Zhidan, Huang, Xueming, Feng, Yajun, Handschin, Christoph, Feng, Yan, Gullicksen, P. Scott, Bare, Olivia, Labow, Mark, Spiegelman, Bruce, Stevenson, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569674/
https://ncbi.nlm.nih.gov/pubmed/16980408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606714103
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