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Fluorogenic metabolic probes for direct activity readout of redox enzymes: Selective measurement of human AKR1C2 in living cells

The current arsenal of tools and methods for the continuous monitoring and imaging of redox metabolic pathways in the context of intact cells is limited. Fluorogenic substrates allow for direct measurement of enzyme activity in situ; however, in contrast to proteases and exo-glycosidases, there are...

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Detalhes bibliográficos
Main Authors: Yee, Dominic J., Balsanek, Vojtech, Bauman, David R., Penning, Trevor M., Sames, Dalibor
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569159/
https://ncbi.nlm.nih.gov/pubmed/16938874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604672103
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