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Photobiological studies with dioxetanes in isolated DNA, bacteria, and mammalian cells.

1,2-Dioxetanes, efficient chemical sources of triplet excited carbonyl compounds, were observed to be genotoxic in isolated DNA, bacteria, and cultured mammalian cells. In superhelical DNA of bacteriophage PM2, various alkyl- and hydroxyalkyl-substituted dioxetanes (1) induced predominantly endonucl...

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Detalhes bibliográficos
Main Authors: Adam, W, Beinhauer, A, Mosandl, T, Saha-Möller, C, Vargas, F, Epe, B, Müller, E, Schiffmann, D, Wild, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568003/
https://ncbi.nlm.nih.gov/pubmed/2125562
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