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The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications
We have analyzed the effects of gene activation on chromatin conformation throughout an ≈170-kb region comprising the human fragile X locus, which includes a single expressed gene, FMR1 (fragile X mental retardation 1). We have applied three approaches: (i) chromosome conformation capture, which ass...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567902/ https://ncbi.nlm.nih.gov/pubmed/16891414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605343103 |
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