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The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications

We have analyzed the effects of gene activation on chromatin conformation throughout an ≈170-kb region comprising the human fragile X locus, which includes a single expressed gene, FMR1 (fragile X mental retardation 1). We have applied three approaches: (i) chromosome conformation capture, which ass...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gheldof, Nele, Tabuchi, Tomoko M., Dekker, Job
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567902/
https://ncbi.nlm.nih.gov/pubmed/16891414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605343103
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