p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB
The tumor suppressor p53 is a transcription factor that controls cellular growth and proliferation. p53 targets include RNA polymerase (pol) III-dependent genes encoding untranslated RNAs such as tRNA and 5S rRNA. These genes are repressed through interaction of p53 with TFIIIB, a TATA-binding prote...
שמור ב:
| הוצא לאור ב: | EMBO J |
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| Principais autores: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2003
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12773395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg265 |
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