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Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76

SH3 domains are protein recognition modules within many adaptors and enzymes. With more than 500 SH3 domains in the human genome, binding selectivity is a key issue in understanding the molecular basis of SH3 domain interactions. The Grb2-like adaptor protein Mona/Gads associates stably with the T-c...

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Published in:EMBO J
Main Authors: Harkiolaki, Maria, Lewitzky, Marc, Gilbert, Robert J.C., Jones, E.Yvonne, Bourette, Roland P., Mouchiroud, Guy, Sondermann, Holger, Moarefi, Ismail, Feller, Stephan M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12773374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg258
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