Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76

SH3 domains are protein recognition modules within many adaptors and enzymes. With more than 500 SH3 domains in the human genome, binding selectivity is a key issue in understanding the molecular basis of SH3 domain interactions. The Grb2-like adaptor protein Mona/Gads associates stably with the T-c...

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Huvudupphovsmän: Harkiolaki, Maria, Lewitzky, Marc, Gilbert, Robert J.C., Jones, E.Yvonne, Bourette, Roland P., Mouchiroud, Guy, Sondermann, Holger, Moarefi, Ismail, Feller, Stephan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC156755/
https://ncbi.nlm.nih.gov/pubmed/12773374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg258
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