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Production of MPS VII mouse (Gus(tm(hE540A)(·)(mE536A)Sly)) doubly tolerant to human and mouse β-glucuronidase
Mucopolysaccharidosis VII (MPS VII, Sly syndrome) is an autosomal recessive lysosomal storage disease caused by β-glucuronidase (GUS) deficiency. A naturally occurring mouse model of that disease has been very useful for studying experimental approaches to therapy. However, immune responses can comp...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567498/ https://ncbi.nlm.nih.gov/pubmed/12700165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddg119 |
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