Production of MPS VII mouse (Gus(tm(hE540A)(·)(mE536A)Sly)) doubly tolerant to human and mouse β-glucuronidase

Mucopolysaccharidosis VII (MPS VII, Sly syndrome) is an autosomal recessive lysosomal storage disease caused by β-glucuronidase (GUS) deficiency. A naturally occurring mouse model of that disease has been very useful for studying experimental approaches to therapy. However, immune responses can comp...

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Bibliografische gegevens
Hoofdauteurs: Tomatsu, Shunji, Orii, Koji O., Vogler, Carole, Grubb, Jeffrey H., Snella, Elizabeth M., Gutierrez, Monica, Dieter, Tatiana, Holden, Christopher C., Sukegawa, Kazuko, Orii, Tadao, Kondo, Naomi, Sly, William S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2003
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567498/
https://ncbi.nlm.nih.gov/pubmed/12700165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddg119
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