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The cytochromes P450 and mechanisms of chemical carcinogenesis.
This article reviews mechanisms of chemical carcinogenesis, from metabolic activation and generation of reactive oxygen species by cytochromes P4511 and P4502E to DNA damage, activation of protein kinase C and ocogenes, hyperplasia, and proteoglycan changes in the cell glycocalyx and lysosomal enzym...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1994
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567360/ https://ncbi.nlm.nih.gov/pubmed/9644192 |
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