Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance

Suppression subtractive hybridization performed on Down syndrome (DS) fetal brains revealed a differentially expressed gene, FABP7, mapped to 6q22–23. FABP7 overexpression in DS brains was verified by real-time PCR (1.63-fold). To elucidate the molecular basis of FABP7 overexpression and establish t...

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Huvudupphovsmän: Sánchez-Font, Ma Francisca, Bosch-Comas, Anna, Gonzàlez-Duarte, Roser, Marfany, Gemma
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC156729/
https://ncbi.nlm.nih.gov/pubmed/12771203
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