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Identification of endogenous electrophiles by means of mass spectrometric determination of protein and DNA adducts.

Monitoring exposure to alkylating agents may be achieved by quantitatively determining the adduct levels formed with nucleic acids and/or proteins. One of the most significant results arising from the application of this approach has been the discovery in control populations of "background"...

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Autors principals: Farmer, P B, Bailey, E, Naylor, S, Anderson, D, Brooks, A, Cushnir, J, Lamb, J H, Sepai, O, Tang, Y S
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567039/
https://ncbi.nlm.nih.gov/pubmed/8319621
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