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Identification of endogenous electrophiles by means of mass spectrometric determination of protein and DNA adducts.

Monitoring exposure to alkylating agents may be achieved by quantitatively determining the adduct levels formed with nucleic acids and/or proteins. One of the most significant results arising from the application of this approach has been the discovery in control populations of "background"...

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Dettagli Bibliografici
Autori principali: Farmer, P B, Bailey, E, Naylor, S, Anderson, D, Brooks, A, Cushnir, J, Lamb, J H, Sepai, O, Tang, Y S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567039/
https://ncbi.nlm.nih.gov/pubmed/8319621
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