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Detection and characterization of DNA adducts at the femtomole level by desorption ionization mass spectrometry.

Current methodologies for the detection and isolation of carcinogen-DNA adducts have advanced beyond the capabilities of the methods used to elucidate their structures. This difficulty seriously limits the potential use of DNA-carcinogen adducts in human dosimetry. We have investigated two general s...

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Autori principali: Lay, J O, Chiarelli, M P, Bryant, M S, Nelson, R W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567028/
https://ncbi.nlm.nih.gov/pubmed/8319622
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