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Hemoglobin adducts of N-substituted aryl compounds in exposure control and risk assessment.

Arylamines, nitroarenes, and azo dyes yield a common type of metabolite, the nitroarene, which produces a hydrolyzable adduct with protein and is closely related to the critical, ultimate toxic and genotoxic metabolite. The target dose as measured by hemoglobin adducts in erythrocytes reflects not o...

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Détails bibliographiques
Auteurs principaux: Neumann, H G, Birner, G, Kowallik, P, Schütze, D, Zwirner-Baier, I
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567010/
https://ncbi.nlm.nih.gov/pubmed/8319661
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