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Hemoglobin adducts of N-substituted aryl compounds in exposure control and risk assessment.

Arylamines, nitroarenes, and azo dyes yield a common type of metabolite, the nitroarene, which produces a hydrolyzable adduct with protein and is closely related to the critical, ultimate toxic and genotoxic metabolite. The target dose as measured by hemoglobin adducts in erythrocytes reflects not o...

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Detalhes bibliográficos
Main Authors: Neumann, H G, Birner, G, Kowallik, P, Schütze, D, Zwirner-Baier, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567010/
https://ncbi.nlm.nih.gov/pubmed/8319661
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