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Active intestinal elimination of ciprofloxacin in rats: modulation by different substrates

1. Two in vivo models, in the rat, were used to investigate, in the presence of different substrates, the overall and net intestinal elimination of ciprofloxacin: an open-intestinal perfusion model and an intestinal loop model respectively. 2. In the presence of quinidine, verapamil and cyclosporin...

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Detalhes bibliográficos
Main Authors: Dautrey, S, Felice, K, Petiet, A, Lacour, B, Carbon, C, Farinotti, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566149/
https://ncbi.nlm.nih.gov/pubmed/10455332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702703
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