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Structural and ionic determinants of 5-nitro-2-(3-phenylpropylamino)-benzoic acid block of the CFTR chloride channel

1. The goals of this study were to identify the structural components required for arylaminobenzoate block of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel and to determine the involvement of two positively charged amino acid residues, found within the channel, in d...

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Autori principali: Walsh, Kenneth B, Long, Kathryn J, Shen, Xufeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566034/
https://ncbi.nlm.nih.gov/pubmed/10385235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702562
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