Nitric oxide synthase inhibition by dimaprit and dimaprit analogues

1. The similarity in molecular structure between the histamine H(2)-agonist dimaprit (3-dimethylamino-propyl-isothiourea) and the endogenous nitric oxide synthase (NOS) substrate L-arginine prompted us to study the effect of dimaprit and some dimaprit analogues on NOS activity. Dimaprit and some of...

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Autors principals: Paquay, Jos B G, 't Hoen, Peter A Chr, Voss, Hans-Peter, Bast, Aalt, Timmerman, Henk, Haenen, Guido R M M
Format: Artigo
Idioma:Inglês
Publicat: 1999
Matèries:
Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566025/
https://ncbi.nlm.nih.gov/pubmed/10385230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702552
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