Characterization of rabbit myocilin: Implications for human myocilin glycosylation and signal peptide usage

BACKGROUND: Mutations in the gene encoding human myocilin (MYOC) have been shown to cause juvenile- and adult-onset glaucoma. In addition, myocilin has been associated with glucocorticoid-induced ocular hypertension and steroid-induced glaucoma. To better understand the role myocilin plays in steroi...

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Bibliografski detalji
Glavni autori: Shepard, Allan R, Jacobson, Nasreen, Sui, Ruifang, Steely, H Thomas, Lotery, Andrew J, Stone, Edwin M, Clark, Abbot F
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2003
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC156599/
https://ncbi.nlm.nih.gov/pubmed/12697062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-5
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