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Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs

1. In this study we describe experiments to establish ex vivo the selectivity of non-steroidal anti-inflammatory drugs (NSAIDs) given in vivo. 2. Anaesthetised (Inactin, 120 mg kg(−1)) male Wistar rats (220–250 g) received an i.v. dose of one of the following compounds (dose mg kg(−1)): aspirin (20)...

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Autors principals: Giuliano, Francesco, Warner, Timothy D
Format: Artigo
Idioma:Inglês
Publicat: 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565969/
https://ncbi.nlm.nih.gov/pubmed/10372826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702518
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