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Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs
1. In this study we describe experiments to establish ex vivo the selectivity of non-steroidal anti-inflammatory drugs (NSAIDs) given in vivo. 2. Anaesthetised (Inactin, 120 mg kg(−1)) male Wistar rats (220–250 g) received an i.v. dose of one of the following compounds (dose mg kg(−1)): aspirin (20)...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1999
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565969/ https://ncbi.nlm.nih.gov/pubmed/10372826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702518 |
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