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Kinetics of rate-dependent shortening of action potential duration in guinea-pig ventricle; effects of I(K1) and I(Kr) blockade

1. The kinetics of shortening of action potential duration (APD) following an increase in pacing rate, from 2 to 3.3 Hz, was characterized in guinea-pig ventricular preparations. Terikalant (RP62719), an inhibitor of the inwardly rectifying K(+) current (I(K1)), and dofetilide, a specific inhibitor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Williams, Beatrice A, Dickenson, David R, Beatch, Gregory N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565915/
https://ncbi.nlm.nih.gov/pubmed/10217537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702443
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