Activation of three types of voltage-independent Ca(2+) channel in A7r5 cells by endothelin-1 as revealed by a novel Ca(2+) channel blocker LOE 908

1. We have shown that in addition to voltage-operated Ca(2+) channel (VOC), endothelin-1 (ET-1) activates two types of Ca(2+)-permeable nonselective cation channel (NSCC) in A7r5 cells: its lower concentrations (⩽1 nM; lower [ET-1]) activate only an SK&F 96365-resistant channel (NSCC-1), whereas...

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Detalhes bibliográficos
Main Authors: Iwamuro, Yasushi, Miwa, Soichi, Zhang, Xiao-Feng, Minowa, Tetsuya, Enoki, Taijiro, Okamoto, Yasuo, Hasegawa, Hiroshi, Furutani, Hidekatsu, Okazawa, Makoto, Ishikawa, Masatsune, Hashimoto, Nobuo, Masaki, Tomoh
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565887/
https://ncbi.nlm.nih.gov/pubmed/10204997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702416
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