Dependency of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels

1. The subcellular mechanisms regulating stimulus-contraction coupling in detrusor remain to be determined. We used Ca(2+)-free solutions, Ca(2+) channel blockers, cyclopiazonic acid (CPA), and RhoA kinase (ROK) inhibitors to test the hypothesis that Ca(2+) influx and Ca(2+) sensitization play prima...

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Detalhes bibliográficos
Main Authors: Jezior, James R, Brady, Jeffrey D, Rosenstein, Daniel I, McCammon, Kurt A, Miner, Amy S, Ratz, Paul H
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572931/
https://ncbi.nlm.nih.gov/pubmed/11522599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704241
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