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Inverse agonist activity of pirenzepine at M(2) muscarinic acetylcholine receptors
1. The intrinsic properties of muscarinic ligands were studied through their binding properties and their abilities to modulate the GTPase activity of G proteins coupled to muscarinic M(2) receptors in pig atrial sarcolemma. 2. Competition binding experiments were performed with [(3)H]-oxotremorine-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565883/ https://ncbi.nlm.nih.gov/pubmed/10205015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702407 |
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