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Inhibitory effect of digoxin on testosterone secretion through mechanisms involving decreases of cyclic AMP production and cytochrome P450(scc) activity in rat testicular interstitial cells
1. In vivo and in vitro experiments were performed to examine inhibitory effects of digoxin on testosterone secretion and to determine possible underlying mechanisms. 2. A single intravenous injection of digoxin (1 μg kg(−1)) decreased the basal and human chorionic gonadotropin (hCG)-stimulated plas...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565747/ https://ncbi.nlm.nih.gov/pubmed/9886754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702229 |
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