Characterization of a prostanoid EP(3)-receptor in guinea-pig aorta: partial agonist action of the non-prostanoid ONO-AP-324

1. Contraction of guinea-pig isolated aorta induced by the prostaglandin E analogue sulprostone (1–400 nM) has a lower maximum response (40%) than that of phenylephrine or U-46619 (TP-receptor agonist). A prostanoid EP(3)-receptor subtype is involved based on agonist potency ranking: equi-effective...

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Detalhes bibliográficos
Main Authors: Jones, Robert L, Qian, Yue-ming, Chan, Kam-ming, Yim, Anthony P C
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565698/
https://ncbi.nlm.nih.gov/pubmed/9863659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702189
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