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Mechanism of voltage- and use-dependent block of class A Ca(2+) channels by mibefradil

1. The action of mibefradil was studied on wild type class A calcium (Ca(2+)) channels and various class A/L-type channel chimaeras expressed in Xenopus oocytes. The mechanism of Ca(2+) channel block by mibefradil was evaluated with two microelectrode voltage clamp. 2. Resting-state dependent block...

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Autors principals: Aczél, S, Kurka, B, Hering, S
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565645/
https://ncbi.nlm.nih.gov/pubmed/9806326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702092
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