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Essential role for endothelin ET(B) receptors in fever induced by LPS (E. coli) in rats
1. The influence of endothelin receptor antagonists on febrile responses to E. coli lipopolysaccharide (LPS), interleukin-1β (IL-1β), tumour necrosis factor-α (TNF-α) and endothelin-1 (ET-1) was assessed in conscious rats. 2. Intravenous (i.v.) LPS (5.0 μg kg(−1)) markedly increased rectal temperatu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565640/ https://ncbi.nlm.nih.gov/pubmed/9806338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702075 |
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