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Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay

1. The newly discovered neuropeptide nociceptin (NC) has recently been reported to be the endogenous ligand of the opioid-like orphan receptor. Despite its structural similarity to opioids, when injected intracerebroventricularly (i.c.v.) in the mouse, NC exerts a direct hyperalgesic effect and reve...

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Hlavní autoři: Calò, G, Rizzi, A, Marzola, G, Guerrini, R, Salvadori, S, Beani, L, Regoli, D, Bianchi, C
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565633/
https://ncbi.nlm.nih.gov/pubmed/9786511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702087
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