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Tumour necrosis factor-α as a target of melanocortins in haemorrhagic shock, in the anaesthetized rat
The cytokine tumour necrosis factor-α (TNF-α) is involved (mostly through the activation of inducible nitric oxide synthase) in the pathogenesis of circulatory shock. On the other hand, melanocortin peptides are potent and effective in reversing haemorrhagic shock, both in animals (rat, dog) and in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565580/ https://ncbi.nlm.nih.gov/pubmed/9756372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702038 |
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