Tacrolimus suppresses tumour necrosis factor-α and protects against splanchnic artery occlusion shock

1. Tumour necrosis factor (TNF-α) is a pleiotropic cytokine which is deeply involved in the pathogenesis of splanchnic artery occlusion (SAO) shock. Tacrolimus, formerly known as FK506, is a macrolide antibiotic, that blocks the transcription of several proinflammatory cytokines including TNF-α. 2....

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Autors principals: Squadrito, Francesco, Altavilla, Domenica, Squadrito, Giovanni, Ferlito, Marcella, Campo, Giuseppe M, Arlotta, Mariarita, Grimaldi, Serafino, Quartarone, Cristina, Saitta, Antonino, Caputi, Achille P
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566016/
https://ncbi.nlm.nih.gov/pubmed/10385251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702528
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