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The role of α(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat
1. The mechanism underlying the anticataleptic properties of the atypical neuroleptic agent, clozapine, has been investigated in the rat. 2. The close structural analogues of clozapine, loxapine (0.1 mg kg(−1) s.c.) and iso-clozapine (1 and 3 mg kg(−1) s.c.) induced catalepsy in rats. In contrast, c...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565533/ https://ncbi.nlm.nih.gov/pubmed/9723970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701975 |
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