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The role of α(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat
1. The mechanism underlying the anticataleptic properties of the atypical neuroleptic agent, clozapine, has been investigated in the rat. 2. The close structural analogues of clozapine, loxapine (0.1 mg kg(−1) s.c.) and iso-clozapine (1 and 3 mg kg(−1) s.c.) induced catalepsy in rats. In contrast, c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565533/ https://ncbi.nlm.nih.gov/pubmed/9723970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701975 |
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