Inhibition of tumour necrosis factor and reversal of endotoxin-induced shock by U-83836E, a 'second generation' lazaroid in rats

1. Antioxidants can exert protective effects in endotoxic shock by either a reduction of the oxidant damage or attenuation of Tumour Necrosis Factor (TNF-α) production. 2. Lazaroids are a family of compounds that inhibit lipid peroxidation. Besides, they can also reduce TNF-α. U-83836E is a new laza...

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Main Authors: Altavilla, Domenica, Squadrito, Francesco, Serrano, Micaela, Campo, Giuseppe M, Squadrito, Giovanni, Arlotta, Mariarita, Urna, Giuseppe, Sardella, Aurora, Saitta, Antonino, Caputi, Achille P
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565499/
https://ncbi.nlm.nih.gov/pubmed/9720803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701944
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