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The anticonvulsant actions of σ receptor ligands in the Mg(2+)-free model of epileptiform activity in rat hippocampal slices

1. The anticonvulsant potency of a series of structurally-dissimilar compounds which possess nanomolar affinities for high-affinity σ binding sites was examined in the Mg(2+)-free model of epileptiform activity in rat hippocampal slices. Extracellular field potential recordings in the CA1 region wer...

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Bibliographic Details
Main Authors: Thurgur, Claire, Church, John
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565460/
https://ncbi.nlm.nih.gov/pubmed/9692777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701902
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