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Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices

1. Hippocampal slices (450 μm) generate epileptiform bursts of an interictal nature when perfused with a zero magnesium medium containing 4-aminopyridine (50 μM). The effect of adenine nucleotides on this activity was investigated. 2. ATP and adenosine depressed this epileptiform activity in a conce...

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Detalhes bibliográficos
Main Authors: Ross, F M, Brodie, M J, Stone, T W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565143/
https://ncbi.nlm.nih.gov/pubmed/9484856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701586
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