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Inhibition of the ATP-sensitive potassium channel from mouse pancreatic β-cells by surfactants
1. We have used patch-clamp methods to study the effects of the detergents, Cremophor, Tween 80 and Triton X100 on the K(ATP) channel in the pancreatic β-cell from mouse. 2. All three detergents blocked K(ATP) channel activity with the following order of potency: Tween 80 (K(i)<∼83 nM)>Triton...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565413/ https://ncbi.nlm.nih.gov/pubmed/9647478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701858 |
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