Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT(6) receptors

1. This study describes the in vitro characterization of two potent and selective 5-HT(6) receptor antagonists at the rat and human recombinant 5-HT(6) receptor. 2. In binding assays with [(3)H]-LSD, 4-amino-N-(2,6 bis-methylamino-pyrimidin-4-yl)-benzene sulphonamide (Ro 04-6790) and 4-amino-N-(2,6...

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Bibliografiske detaljer
Main Authors: Sleight, Andrew J, Boess, Frank G, Bös, Michael, Levet-Trafit, Bernard, Riemer, Claus, Bourson, Anne
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565407/
https://ncbi.nlm.nih.gov/pubmed/9647481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701851
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