Two imidazoquinoxaline ligands for the benzodiazepine site sharing a second low affinity site on rat GABA(A) receptors but with the opposite functionality

1. Imidazoquinoxaline PNU-97775 and imidazoquinoline PNU-101017 are benzodiazepine site ligands with a second low affinity binding site on GABA(A) receptors, the occupancy of which at high drug concentrations reverses their positive allosteric activity via the benzodiazepine site, and may potentiall...

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Detalhes bibliográficos
Main Authors: Im, Haesook K, Bin Im, Wha, Pregenzer, Jeffrey F, Stratman, Nancy C, VonVoigtlander, Philip F, Jon Jacobsen, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565320/
https://ncbi.nlm.nih.gov/pubmed/9605552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701763
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