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Elevated plasma endothelin-1 level in streptozotocin-induced diabetic rats and responsiveness of the mesenteric arterial bed to endothelin-1

1. Both the plasma endothelin-1 (ET-1) levels and the plasma glucose levels were markedly elevated in streptozotocin (STZ)-induced diabetic rats. 2. The maximum contractile response of the mesenteric arterial bed to ET-1 was significantly reduced, and the vasodilatation induced by the ET(B)-receptor...

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Detalhes bibliográficos
Main Authors: Makino, Ayako, Kamata, Katsuo
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565260/
https://ncbi.nlm.nih.gov/pubmed/9559887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701704
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