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A comparative study on the rat aorta and mesenteric arterial bed of the possible role of nitric oxide in the desensitization of the vasoconstrictor response to an α(1)-adrenoceptor agonist

1. In thoracic aortic strips with intact endothelium, the first and second (1 h later) dose-response curves obtained with methoxamine were almost the same. 2. Methoxamine caused a dose-dependent increase in perfusion pressure in the rat isolated mesenteric arterial bed, but the second (1 h later) do...

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Detalhes bibliográficos
Main Authors: Kamata, Katsuo, Makino, Ayako
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564594/
https://ncbi.nlm.nih.gov/pubmed/9105696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701031
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