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Regulation of H(1)-receptor coupling and H(1)-receptor mRNA by histamine in bovine tracheal smooth muscle

1. Pretreatment of bovine tracheal smooth muscle (BTSM) with histamine (1–100 μM, 1 h) induced a concentration-dependent desensitization of the contractile response to subsequently administered histamine, with a reduction of the maximum response of 72±8% (n=5) following pre-exposure to 100 μM histam...

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Dettagli Bibliografici
Autori principali: Pype, J L, Dupont, L J, Mak, J C W, Barnes, P J, Verleden, G M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565248/
https://ncbi.nlm.nih.gov/pubmed/9535029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701697
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