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Induction of nitric oxide synthase by protein synthesis inhibition in aortic smooth muscle cells

1. The role of de novo protein synthesis in inducible NO synthase (iNOS) activation was investigated in vitro by evaluating the effects of protein synthesis inhibitors cycloheximide (CH) and anisomycin (ANI) on iNOS activity, protein and mRNA levels in rat aortic smooth muscle cells (RASMC). 2. As d...

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Autori principali: Marczin, Nándor, Go, Carolyn Y, Papapetropoulos, Andreas, Catravas, John D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565241/
https://ncbi.nlm.nih.gov/pubmed/9535031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701687
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