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Effects of rolipram on cyclic AMP levels in alveolar macrophages and lipopolysaccharide-induced inflammation in mouse lung

1. Our previous work demonstrated that bacterial lipopolysaccharide (LPS), administered by aerosol, induced tumour necrosis factor (TNF-α) synthesis leading to the infiltration of neutrophils into mice lungs. The treatment of animals with prostaglandin E(2) or dibutyryl cyclic AMP impaired both proc...

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Detalhes bibliográficos
Main Authors: Lucia Gonçalves de Moraes, Vera, Singer, Monique, Boris Vargaftig, B, Chignard, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565207/
https://ncbi.nlm.nih.gov/pubmed/9517381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701649
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