Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase

1. The haeme-containing soluble guanylyl cyclase (α(1)β(1)-heterodimer) is a major intracellular receptor and effector for nitric oxide (NO) and carbon monoxide (CO) and mediates many of their biological actions by increasing cyclic GMP. We have synthesized new oxadiazolo-benz-oxazins and have asses...

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Detalhes bibliográficos
Main Authors: Olesen, Søren-Peter, Drejer, Jørgen, Axelsson, Oskar, Moldt, Peter, Bang, Lone, Nielsen-Kudsk, Jens Erik, Busse, Rudi, Mülsch, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565161/
https://ncbi.nlm.nih.gov/pubmed/9489619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701603
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