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Efficacy of inverse agonists in cells overexpressing a constitutively active β(2)-adrenoceptor and type II adenylyl cyclase
1. Maximal stimulant output from the adenylyl cyclase cascade in neuroblastoma × glioma hybrid, NG108-15, cells is limited by the levels of expression of isoforms of adenylyl cyclase. Stable expression in these cells of a constitutively active mutant (CAM) version of the human β(2)-adrenoceptor resu...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1998
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565159/ https://ncbi.nlm.nih.gov/pubmed/9489623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701600 |
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